This bug persist on the Guix version I'm using: ★★★★★★★★★★ $ guix describe Generation 4 Jul 05 2020 13:40:24 (current) guix 6ee7468 repository URL: https://git.savannah.gnu.org/git/guix.git branch: master commit: 6ee7468758d7c043692ae8c0b5e130fa4eabe94c ★★★★★★★★★★ There is one thing I hadn't noticed before, though. If I insert a DVD while I'm in a GNOME session, it doesn't work (that's the bug), but if I reboot with the DVD still in, log in to GNOME and open Nautilus, the DVD is listed and it works correctly. After doing this, if I extract the DVD and insert it again, it still doesn't work.